Analysis of cytochrome P450 and phase II conjugating enzyme expression in adult male rat hepatocytes

mainly discussing the effects MRSA infection affects cyp450 in turn leading to possible drug interactions which may lead to toxic effects.
I started but it requires a lot for work. Davila on the work cited is the main paper
. Your second draft should be 15 to 20 word–processed pages. You must use a minimum of 15 references, of which at least 10 are from the primary literature. Except for the cover page, your draft must have all of the components of the final monograph including the table of contents and the bibliography. Only the written portion of your monograph is to be submitted to Turnitin.

Mapping toxic waste sites

All assignments must include the following
Organize your report in the format of a scientific lab report. Use the instructions on pages 3-4 of the urban ecology handout Download the urban ecology handoutfor a list of the sections and their content.
Your introduction must include at least two external sources that provide background information on your topic. These can be general background information (the “context” part of the introduction) or something more specific to your study system.
Add a Literature Cited section to the end of your report with proper formatting of all your citations (APA format or similar).
Mapping toxic waste sites
Choose one of the following two options for increasing your sample size
Focus on one city: Collect data from at least ten locations in your city for each of the four combinations of race and income.
Compare across cities: Choose three cities that you think are different from each other. Collect data from at least four locations in each city for each of the four combinations of race and income.
Present your data in a data table that clearly shows the comparisons you are making. The format of the table will vary a little bit depending on the type of comparison you chose in the previous step. Give your table a caption that explains the results of your comparison.
Follow all the other instructions under “All assignments must include the following.”
Justice map: http://www.justicemap.org/
Cleanups: https://ordspub.epa.gov/ords/cimc/f?p=cimc:map::::71
Cleanups: https://cimc.epa.gov/ords/cimc/f?p=CIMC:LIST
Redlining: https://dsl.richmond.edu/panorama/redlining/#loc=5/39.1/-94.58

Week 3 CRISPR

To demonstrate your proficiency and effectiveness in analyzing, evaluating and integrating reliable sources into your Final Capstone Project, you will create a presentation highlighting your selected sources. You will select three sources you have chosen for your final paper and create a presentation (Power Point or Word document are acceptable). Each source should support one of the three supporting claims in your thesis (One source for each supporting claim). Peer-reviewed scholarly sources from the library databases are required.
Required Information for Each Source
APA formatted reference
Rationale: Align each source with one supporting claim
Summary (150 words) Briefly describe the source and evidence
Credibility (150 words) Briefly support your choice of this source by answering the following questions.
Currency
Relevance
Accurate
Authority
Purpose
This week’s discussion is a peer-review of the Research Project: Annotated Bibliography. Be sure to post the Annotated Bibliography as a discussion post and as a submission for a grade in the Week Three Research Project area.
For your initial post, share the Research Presentation created for this week’s assignment. If it is a Word Document please paste your presentation directly into the Discussion text box, Power Points can be posted as attachments.
For your peer responses: Choose two peers and assess the overall effectiveness and their assessment of the source. Specifically, address the following points:

Is the source accurately formatted in APA 7th edition?
Is the alignment to a specific supporting claim clear for each source?
Is the summary provide enough information to understand the main idea?
Has credibility been established by specifically addressing the following criteria?
Currency
Relevance
Accurate
Authority
Purpose
E. Share at least one suggestion or recommendation on the research presented.

Qualitative Research

This will be a written assignment for my doctoral qualitative research class.
For this particular assignment, respond to the following topic:
For this assignment you will code narrative data to answer a research question: “How do doctoral students in RES 7700 perceive and understand their experiences with education and educative processes?” Narratives were submitted in Week 1 which you will work to code. The coding scheme that you will develop must lead you to answering this specific research question.You will be reading and ‘makingsense’ out of these narratives through the lens of ‘what can these narratives tell you about the research question? ’Another way to this about this is that you will be interrogating the narratives with this research question. Also, you must use Word or Excel to code the transcriipts and create the Code Book. You can use highlighting, color-coding, annotation, comment function, tables, etc. If you do your coding by hand on paper with pencil, you will need to transfer this into a Word file. You will be asked to include the coded transcriipts to the final paper. The report must include:
* A research question.
* The transcriipts with the coding process (i.e., original text unitized; category codes; sorting of 
the categories into themes, and possibly relationships between themes).
* The coding scheme: explanation of your codes.
* Summary of your findings: What did you learn so far about your research question? Work to connect your claims here to the language in the narratives.
* MEMO A: An explanation of how you moved from your codes to your findings and your 
coding process.
* MEMO B: What do you think about coding? Where do you see gaps in your data? How does what you learned inform your thinking about your interview/observation data?
* A list of references that back up all in-text citations. Be sure to use APA.
For your reference, I am a healthy, white 34-year old female from Kentucky. I am extremely active and spend a lot of time working out and eating healthy food. Also, I am a college professor in the Exercise Science department and own an online fitness and nutrition coaching business.
I have attached a copy of the assignment details, as well as the narrative transcriipt that will be used for this assignment. There are also 2 examples provided of how the coding should be completed and put into words. Also, I have attached the book chapters and recommended resources to elaborate on the course material discussed during this section.

Rare genetic Variant (CISD2) in relation to Wolfram Syndrome 2

Title: Identification and characterisations of rare genetic variants (CISD2) in a group of NHS patients being treated for severe obesity.
The results data for this dissertation can be found at https://wetransfer.com/downloads/77c9f7e19c62d9dbc5332effb46f810420221117020410/7a12ac?utm_campaign=TRN_TDL_05&utm_source=sendgrid&utm_medium=email&trk=TRN_TDL_05
I need the writer to do the full dissertation and I want him to explain me how he uses Python software to interpret the results and construct the graphs.
Methodology: 

– Use e a test of proportions to check whether the frequency of a particular variant in the PMMO differs from its frequency in the general population (gnomAD controls). 

– Check the reliability of the genotyping by visual examination of cluster plots. If the cluster plots are convincing then annotate these variants to assess how they might exert their effects by Combined Annotation Dependent Depletion (CADD score).
– Determine what the gene does, according to the literature. Are there already disease/phenotypic associations in humans or animal models?
– Looking at the gene variants in the PMMO dataset: are there mutation carriers in the PMMO? – Are the variants over- or under-represented in the PMMO compared to gnomAD controls?
– Annotation of the variants – what type of mutation is? does it affect an amino acid – how? where in the protein does it occur? What is the evidence that this mutation may affect function?
If time allows, repeat this analysis with related genes.
Layout: (Explained in the assessment brief attached under the files section)
– Abstract
– Introduction
– Aims
– Methods
– Results
– Discussion
– General Matters

Searching and Evaluating Scientific and/or Mathematical/Analytical Resources

This week, you will find three scholarly, peer-reviewed research articles on your topic. Remember that next week you will submit a paper on Scientific and/or Mathematical/Analytical perspectives of inquiry, so use this week’s assignment to prepare materials and collect information for that purpose.
Use articles that will help you explain and describe scientific issues and/or statistical data or economic information related to your topic. You will analyze and evaluate these articles in your submission, which should include:
A brief introductory paragraph.
Three separate paragraphs, one for each of the three articles, each presenting:
A brief 3–4 sentence summary of the article (use in-text citations)
An explanation as to what makes this source credible (in the WCU Library go to Research Guides > Research Basics > Evaluating Resources)
An explanation of why the article will be useful in addressing your problem or issue
A brief conclusory paragraph
An APA Style reference list on a separate page
Your paper should be 1–3 pages in length (including the References page). Adhere to APA Style throughout.
Review the rubric for further information on how your assignment will be graded.